Adie Rae, “The liver is responsible for this transformation, and specifically, the drug-metabolizing enzyme known as cytochrome P2C9 or CYP2C9. According to neuroscientist and medical cannabis adviser, Dr.
This process is known as first-pass metabolism. Take THC for example whether you’re consuming Delta 8 or Delta 9, the body processes all tetrahydrocannabinols the same, by converting them to a metabolite known as 11-hydroxy-THC. There are also some individual factors that impact the onset and intensity of the effects, such as the specific cannabinoid consumed or a person’s metabolism. It’s not an instant sensation like the aforementioned alternatives would be and it can take anywhere from 30 minutes to 2 hours to kick in, but the effects last much longer.įood and supplements need to be processed by the liver, meaning more of the cannabinoid will be filtered out of your system because of the slower absorption time. Let’s start with the basics… why do cannabis edibles affect our bodies so differently than smoking or vaping? Just like anything else that goes through our digestive systems, cannabis edibles need to metabolize before the effects can be felt. The difference between edibles and other consumption methods
